- Kaposi's Sarcoma: A report of three cases.
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Yeon Soo Lee, Yeong Jin Choi, Mi Kyung Jee, Seok Jin Kang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1995;29(3):385-390.
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- The classic type of Kaposi's sarcoma, or multifocal hemorrhagic sarcoma histologically characterized by proliferating fibroblastic and microvascular elements was described by Kaposi as a relatively rare neoplasm. During the past nine years, we experienced three cases of sporadic, classic Kaposi's sarcomas. They were presented as multiple papules, macules and nodules on the skin of the hands, lower logs and feet without systemic involvement. Histologically, Kaposi's sarcoma is divided into three stages, early patch, plaque and nodular stages. The nodular lesions(case 1, 2 and 3) showed extensive proliferatiion of spindle shaped, somewhat pleomorphic cells having dark prominent nuclei, proliferation of small vessels with solid aggregates of endothelial cells, and extravasation of erythrocytes. In early patch stage(case 3), widely dilated, anastomosing, thin-walled vascular spaces are noted in the upper half of the dermis. In plaque stage(case I and 3), there are proliferation of spindle shaped cells with extravasated erythrocytes and aggregates of blood vessels lined by prominent endothelial cells.
- Crescentic Glomerulonephritis in a Patient with Rheumatoid Arthritis: A case report.
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Ki Ouk Min, Yeong Jin Choi, Byoung Kee Kim, Sun Moo Kim, Sang In Shim
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Korean J Pathol. 1995;29(1):116-118.
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- Crescentic glomerulonephritis in rheumatoid arthritis is described recently with increasing frequency. It can occur directly as a manifestation of rheumatoid arthritis or may be a reaction to drugs such as D-penicillamine and bucillamine. We report a case of crescentic glomerulonephritis in a 46-year-old woman with rheumatoid arthritis for 20 years who had been treated intermittently with herb medicine or nonsteroidal anti-inflammatory drugs (NSAIDS). Light microscopic examination showed severe focal segmental and global necrotizing glomerulonephritis with crescent formation in 50% of the glomeruli.
Immunofluorescent study revealed scanty amount of mesangial granular deposits of IgA, IgM, C3 and fibrinogen in a diffuse pattern.
- Extraskeletal Osteosarcoma of the Sole: A case report.
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Ki Ouk Min, Mi Kyung Jee, Seok Jin Kang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1993;27(3):279-282.
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- Compared with osteosarcoma of bone, primary osteosarcoma of the soft tissue is very rare. Extraskeletal osteosarcoma is also a highly malignant pleomorphic sarcoma composed of cells exhibiting primarily osteoblastic, and to a lesser extent, chondroblastic differentiation. A case of extraskeletal osteosarcoma in the right sole is presented in a 67 year old male. The patient had noticed a progressively enlarging soft tissue mass, during about 14 months. This sarcoma was located in the soft tissues without attachment to the skeleton, as determined by examination of the X-Ray findings. The mass of right plantar portion was simply excised and pathologically confirmed to be an extraskeletal osteosarcoma. The clinical and pathological features of this sarcoma are described, and brief review of the literature is made.
- Orbital Pseudolymphoma: A case report.
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Su Kyeong Yeon, Mi Kyung Jee, Seok Jin Kang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1993;27(2):191-194.
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- Lymphoid tumors of the orbit are rare, and sometimes it is not possible either clinically or histologically to differentiate between lymphoid tumor and pseudolymphoma.
Some authors assert that the degree of cytologic differentiation appears to be the single most important factor for determining the prognosis of patients with orbital lymphoid lesions. However, the cytomorphologic basis is not so helpful to diagnose and classify our case, which shows some discrepancy between pathological findings and clinical and radiological findings. At first we misdiagnosed our case as orbital malignant lymphoma on the basis of cytomorphology and immunohistochemical study. But no responce to local intensive radiotherapy and the follow up study of the patient suggest orbital pseudolymphoma.
- Trichoadenoma: Report of a case.
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Youn Soo Lee, Mi Kyung Lee, Seok Jin Gang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1993;27(1):75-77.
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- The clinical and pathological features of trichoadenoma are presented. Trichoadenoma is very rare, and as far as we know, no report on the trichoadenoma has been published in korea literature. We experienced a case of trichoadenoma occured in a 29 year-old male, who had a 0.9x0.7x0.4cm sized and slowly growing mass in the right buttock. The histopathological findings and histogenesis of trichoadenoma were discussed and a brief review of the literature was made.
- Sebaceous Epithelioma: A report of 2 cases.
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Youn Soo Lee, Mi Kyoung Jee, Seok Jin Gang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1993;27(1):58-63.
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- Sebaceous epithelioma is a relatively rare tumor, mostly occuring in the face or scalp. The histogenesis and clinical and pathological features of sebaceous epithelioma have not been clearly defined, and a few other diagnostic terms have been used so far instead of sebaceous epithelioma. Two cases of sebacous epitheliomas were presented. No recurrence or metastasis was observed in our cases, so sebaceous epithelioma is considered to be a benign tumor. A brief review of the literature, concerned about the biological behavior, histogenesis and pathological findings of the sebaceous epithelioma, was made.
- Fine needle aspiration cytology of presacral chordoma-a case report-.
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Su Kyeong Yeon, Mi Kyung Jee, Chang Suk Kang, Byoung Kee Kim, Sun Moo Kim, Sang In Sim
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Korean J Cytopathol. 1993;4(2):133-139.
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- No abstract available.
- Rhabdomyosarcoma of the Prostate: Two cases report.
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Kyoung Mee Kim, Ki Hwa Yang, Seok Jin Kang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1992;26(4):394-398.
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- The rhabdomyosarcoma of the prostate is very rarely encountered in the western literature, and only a few reports have been published in Korea. The authours recently experienced two cases of rhabdomyosarcomas of the prostate in 35-year-old and 51-year-old males who had suffered from gross hematuria and difficulty of urination. Microscopic studies showed embryonal type of rhabdomyosarcoma in two cases. The clinical and pathological features of the distinctive prostatic rhabdomyosarcoma are described, and a brief review of the literature is made.
- Agenesis of the Dorsal Pancreas: An autopsy case.
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Won Sang Park, Ki Hwa Yang, Seok Jin Kang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1992;26(1):71-75.
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- Agenesis of the dorsal pancreas is one of the rare congenital anomalies of the pancreas. Six cases of them have been reported. We have experienced an autopsy case of agenesis of the dorsal pancreas associated with fetal death in the uterus. Grossly, the body and tail of the pancreas and uncinate process were not found and those were partially replaced by adipose tissue. No abnormality was noted in the other organs. Microscopically, pancreatic tissue with autolytic change was identified only in the head portion of the pancreas.
- Eccrine Poroma: A report of five cases.
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Young Shin Kim, Seok Jin Kang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1991;25(4):357-362.
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- The eccrine poroma was described first by Pinkus et al. in 1956 as a subgroup of benign solid hidradenoma with the histologic structure resembling acrosyringium. The histologic appearance of eccrine poroma greatly resembles that of seborrheic keratosis and basal cell carcinoma. But the clinical lesion is fairly unique and the tumor is most commonly found almost exclusively on the foot, in the skin of the plantar surface. During the past four years, the authors experienced five cases of eccrine poroma which were diagnosed by histopathological examination of the tumor mass. All the cases occurred in the sole and lateral sides of the foot as well. Clinical and pathological features were reviewed and a brief review of the literatures was done.
- Sarcoidosis Involving the Spinal Dura.
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Young Shin Kim, Ki Hwa Yang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1991;25(2):158-163.
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- Neurosarcoidosis without systemic manifestation is vary unusual condition. Solitary lesion in the spinal dura is exceptional. The diagnosis of the neurosarcoidosis is very difficult, because the efficacy of Kveim test is low in neurosarcoidosis. The histologic examination is considered as confirmative diagnostic tool. The authors reported a case of neurosarcoidosis involving the dura of the cervical spine, in a fifty-nine year old female who had suffered from mid-back pain for six months and paraparesis for two weeks.
There was a dumbbell shaped mass in the D4-5 dura. It showed tan gray color with rubbery consistency. With histological examination, it revealed diffuse non-caseating granuloma.
Occasionally asteroid bodies were observed within the cytoplasm of the multinucleated giant cells. After operation, she was treated with steroid, and she has been well about nine month period.
- Meningioma, Hemangiopericytic Type, with Bone Metastasis: A report of a case.
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Ki Hwa Yang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1991;25(1):59-67.
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- Since Lebert stated, in 1851, that fibroblastic and sarcomatous tumors of the intracranial cavity had different survival times, many neuropathologists tried to set up histopathological grading system predicting the prognosis of the tumor of the nervous system. Especially, the histological assessment of the aggressiveness of meningiomas has not always been useful in conforming the biological characteristics of these tumors, and the definition of malignancy is still subject to controversy. However, metastases from meningioma to remote sites have always been considered rarities. The authors experienced a case of metastatic meningioma, hemangiopericytic type, with a history of recurrence. A forty years old male patient received a craniotomy to remove a mass in right parasagittal region, in June 1981. He had suffered from Jacksonian type of seizure started from left foot throuth leg, thigh, and arm to face. During operation, a well defined mass was noted in left parasagittal region with cleavage plane. The tumor was completely removed with cauterization of invasion site.
In microscopic examination, the mass had typical findings of hemangiopericytic type of meningioma. In September 1987, he received a repeat operation to remove a recurred tumor mass in vertex, at age of forty-six. The removed tumor revealed same histologic features as those seen in primary tumor. In January 1990, at age of forty-nine, he noted pain and tenderness on the right iliac crest and the left iliac tuberosity, Plain pelvis AP x-ray ad Pelvis CT scan revealed osteolytic expansile mass lesions involving both iliac bones, the body of second sacral vertebra, and the right superior ramus of the pelvic bone. An open biopsy of the iliac bone was performed. The microscopic findings of the bone lesion were same as reccruent lesion of the brain.
- Adenoid Squamous Cell Carcinoma of the Vulva: Report of a case.
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Chang Ok Kim, Ki Hwa Yang, Seok Jin Gang, Ahn Hee Lee, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1991;25(1):54-58.
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- In 1947, Liver described adenoid squamous cell carcinoma under the title of "adenoacanthoma of sweat gland". This tumor is not rare, but reported cases in literatures were relatively few. The tumor were frequently found in the sun-exposed skin; such as face, ear, neck etc.. The cases involving non-sun-exposed area, such as oral and labial mucosa, nosopharynx and vulva etc., were also reported.
Therefore, the relation between the pathogenesis of adenoid squamous cell carcinoma and sun damage has been still debated. Immunohistochemical studies have recently suggested that this tumor is squamous cell carcinoma undergoing acantholysis. The authors experienced a case of adenoid squamous cell carcinoma of the vulva in a seventy-one year old female patient. She had suffered from itching sensation on vulva for 10 years, and palpable mass on vulva for 1 month. On gross examination, a pale gray pigmentation and erosion, was noted at the right labia major, the minor extending left labia major and minor. On microscopic examination, nests of atypical epithelial cells extending into the cornium showed an adenoid architecture. These were composed of a peripheral layers of cuboidal cell in a lacy pattern. And the glandular spaces contained dyskeratotic acantholytic tumor cells in central portion. Therefore we diagnosed this case as adenoid squamous cell carcinoma of the vulva.
- Proliferating Trichilemmal Tumor: Report of four cases.
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Yeong Jin Choi, Mi Kyung Jee, Seok Jin Gang, Byoung Kee Kim, Sun Moo Kim, Soo Il Chung
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Korean J Pathol. 1990;24(2):176-182.
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- Proliferating trichilemmal tumor is relatively rare, and is generally considered to be a benign tumor that can be histologically mistaken for well-differentiated squamous cell carcinoma. The proliferating trichilemmal tumor is thought to be a tumor with differentiation toward the hair structure because the characteristic trichilemmal keratinization in this tumor is analogous to that of the outer root sheath of anagen hair or the trichilemmal sac surrounding catagen hair. We report four cases of proliferating trichilemmal tumor removed by surgical excision.
- Spinal Enterogenous Cyst: A report of a case.
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Ki Hwa Yang, Kyo Young Lee, Young Sup Park, Seok Jin Kang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1989;23(4):490-493.
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- Although varying types of cystic lesion, true to false, in the spinal cord have been described, spinal enterogenous cyst is a rare condition. It is considered as a result of congenital remnant of primitive foregut. The authors experienced a case of a spinal enterogenous cyst in the intradural space along the fouth, fifth and sixth cervical spine, occurred in a twenty-seven years old male patient.
The cyst was composed of hyalinized fibrous wall with single layered lining epithelium, such as simple non-ciliated cuboidal epithelium or ciliated tall columnar epithelium with focal mucinous columnar epithelium.
- Primary Meningioma of the Nasal Cavity and Paranasal Sinuses: A report of a case.
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Chang Ok Kim, Mi Kyung Jee, Ki Hwa Yang, Chang Suck Kang, Seok Jin Gang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1989;23(4):461-464.
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- Primary extracranial and extraspinal meningiomas are rare.
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s involving the orbit, skin, nasal cavity, paranasal sinuses, oral cavity and parotid gland have been reported.
The histogenesis of primary extracranial meningioma is still nucertain, but it has been thought that this tumor originates from arachnoid cell rests in displaced during embryonal development. The authors observed a case of primary meningioma of the nasal cavity and paranasal sinuses occurring in a thirty-eight year old male patient in Feb.
1989. He suffered from bulging in the medio-superior portion of left orbit for 15 years, and left nasal obstruction and headache for 5 years, A head CT scan revealed numberous polypoid masses filling the left frontal sinus left ethmoidal sinus, left maxillary sinus and left nasal cavity.
During the operation, a connection to the dura was not found. Microscopically, there were discrete lobules or netst of meningothelial cells, beneath the nasal mucosa. They showed an occasional whorling pattern and psammoma bodies.
Therefore, this case was diagnosed as primary meningioma, meningotheliomatous type involving the left nasal cavity and paranasal sinuses.
- Tumorlet of Lung Associated with Congenital Bronchogenic Cyst: Report of a case.
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Yeong Jin Choi, Mi Kyung Jae, Seok Jin Kang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1989;23(1):141-144.
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- Tumorlet is a rare lesion of disputed origin that was first described by whitwell in 1955, and about one-third of the reported cases have been associated with underlying lung disease. Patient was a 60-year-old female who was admitted with a histroy of chest discomfort and dyspnea. Right lower lobe was partially resected under the clinical diagnosis of the bronchogenic cyst. Grossly, lung tissue around round cystic lesion appeared brown firm and somewhat fibrotic, and showed several scattered ill-defined whitish gray nodules.
Microscopically, lung tissue around bronchogenic cyst was partially obliterated by dense fibrous scar tissue. Within this areas of fibrosis, and in the wall of alveolar ducts and respiratory bronchioles, innumerable microscopic tumorlets were found and argyrophilic granules were also demonstrated in scattered tumorlets with Grimelius stain.
- Mixed Germ Cell Tumor in Third Ventricle: A report of case.
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Ki Hwa Yang, Sung Dae Jin, Eun Jung Lee, Kyo Young Lee, Seok Jin Gang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1988;22(1):118-122.
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- Primary mixed germ cell tumor is a very rare tumor in the cranial cavity. It is composed of varying combination of germ cell neoplasms, such as germinoma, embryonal carcinoma, choriocarcinoma and teratoma. The authors experienced a case of mixed germ cell tumor developing in the floor of the third ventricle, in a twelve years old boy. He was admitted to the hospital, because of headache, eyeball pain, diplopia and vomiting. Brain CAT scan revealed a round tumor density in the floor of the third ventricle. Tumor marker study, preoperatively checked, revealed beta-HCG, 439.8 mIU/ml and alpha-fetoprotein, under 20 ng/ml. On operation, there was a dark brown firm mass up to 3.0 cm in the third ventricle, that invaded into the foramen Monro. With microscopic examination, this tumor is composed chiefly of germinoma, with embryonal carcinomatous region, choriocarcinomatous region and focal mature teratomatous region. The authors diagnosed this case as mixed germ cell tumor.
- Female Adnexal Tumor Probable Wolffian Origin: Report of a case.
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Soo Kyong Chung, Seok Jin Gang, Byoung Kee Kim, Sun Moo Kim
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Korean J Pathol. 1987;21(1):45-48.
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- The clinical and pathological features of a distinctive female adnexal tumor of probable Wolffian origin (FATWO) are presented. As fat as our knowledge is concerned, no report on the FATWO has been published in Korea. In April, 1986, we experienced a case of FATWO that arose within the leaf of the right broad ligament in a 68 years old female. Clinical data and histopathological findings of the case were discussed and a brief review of the literature on this entity was made.
- Burkitt's Lymphoma Developed Acute Leukemia: A report of two cases.
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Young Dae Kim, Kyoung Ja Han, Byoung Kee Kim, Sun Moo Kim
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Korean J Cytopathol. 1985;19(2):207-213.
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- Burkitt's lymphoma with a frankly leukemic picture is an extremely rare condition, and usually has a very acute course with a poor prognosis. The authors experienced two cases of Burkitt's lymphoma developed acute leukemia. The first case was 8 years-old boy who had rapidly growing large abdominal mass, which revealed typical Burkitt's lymphoma with characteristic "starrysky" pattern. The second case was 20 year old male who had not definite tumor mass. Their peripheral blood and bone marrow aspiration revealed acute leukemia with multiple vacuolated lymphoblast of Burkitt's type. We report these cases with brief review of literatures.
- Immature Teratoma of the Ovary with a Fetal Cerebellum: A report of 2 cases.
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Seok Jin Gang, Ki Hwa Yang, Byoung Kee Kim, Sun Moo Kim
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Korean J Cytopathol. 1985;19(1):119-124.
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- During the past 1 year the authors experienced 2 cases of fetal cerebellum in an immature teratomaof the ovary which were diagnosed by the histopathological examination of the tumor mass removed by the surgical operation. The first case was a 15-year-old female. At laparatomy an infant head sized mass at the site of the right ovary was removed. The ovary was replaced by a large, predominantly solid and focally cystic mass which weighed 810 gms. and measured 16x14x11 cm.
The second case was a 10-year-old female. The right ovary was replaced by a large cystic and focally solid mass which weighed 730 gms. and measured 15x13x10 cm. The cystic portion of the tumor was made up to multiloculated cysts filled with serous fluid. Microscopically, the first case showed an abundant mature tissue from the three germ layers, but this was intermixed with small foci of neuroepithelial tubules present in groups. Well formed fetal cerebellar folia(18 folia) characterized by a definite external granular cell layer, molecular layer, Purkinje neurons and an internal granular cell layer was identified. The second case revealed a predominantly mature tissue. Mature elements from the three germ layers were present. There are small foci of immature neural tissue growing largely in the form of neuroepithelial tubules. Fetal cerebellum with well formed folia(13 folia) was also identified. A brief review of the literature and a discussion on the clinicopathological correlations were made.
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